Acetaminophen

Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

Analgesics (Misc.)AcetaminophenNormal dose based on indicationAdminister Anytime During HD

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
151N/A2220-301-2N/AN/A

References:

  • Aronoff GR, Bennett WM, Berns JS, Brier ME, Kasbekar N, Mueller BA, et al. Drug Prescribing in Renal Failure. Philadelphia: American College of Physicians;2007.
  • DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL: http://www.drugbank.ca/drugs/DB00316
  • Lee H, Ti T, Lye W, Khoo W, Tan C. Paracetamol and its metabolites in saliva and plasma in chronic dialysis patients. British Journal of Clinical Pharmacology. 1996;41(1):41-47.