Cefixime
| Drug Category | Drug | IHD Dosing | Administration Timing Around HD Session |
|---|---|---|---|
| Antibiotics | Cefixime | 200mg Q24H | Administer Post-HD |
Molecular Weight (Da) | Excreted Unchanged (%) | Normal Half-Life (Hours) | ESRD Half-Life (Hours) | Plasma Protein Binding (%) | Volume of Distribution (L/kg) | Dialytic Plasma Clearance (ml/min) | % Dialyzed |
|---|---|---|---|---|---|---|---|
| 453 | 18-50 | 3.1 | 12 | 50 | 0.6-1.1 | 0.5 | 0 (low flux) |
References:
- DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL: http://www.drugbank.ca/drugs/DB00671
- Faulkner R, Yacobi A, Barone J, Kaplan S, Silber M. Pharmacokinetic Profile of Cefixime in Man. Pediatric Infectious Diseases Journal 1987; 6, 963-70.
- Guay D, Meatherall R, Harding G, Brown G. Pharmacokinetics of Cefixime (CL 284 , 635 ; FK 027 ) in Healthy Subjects and Patients with Renal Insufficiency. Antimicrobial agents and chemotherapy 1986; 30(3), 485-90.