Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

Antiemetics Dimenhydrinate 25-50 mg Q8H PRN Anytime During HD

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
469.94 N/A  1-4 N/A 98-99 N/A N/A N/A


  • Aronoff GR, Bennett WM, Berns JS, Brier ME, Kasbekar N, Mueller BA, et al. Drug Prescribing in Renal Failure. Philadelphia: American College of Physicians;2007.
  • DrugBank [Online]. 2013 Feb 06 [cited 2013 Feb 06]; Available from: URL: http://www.drugbank.ca/