Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

Calcium Channel BlockersVerapamil180-480mg PO Q24H (sustained release)Administer Anytime During HD; Post HD if Hypotensive

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
455<32.8-7.42.4-483-933-7.127Minimal (low flux)


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