Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

Metabolic Bone Disease MedicationsCinacalcet30-180mg PO Q24HAdminister Anytime During HD

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
357<130-40N/A93-9714.2 (based on 70 kg)N/AN/A


  • DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL:
  • Padhi D, Harris R. Clinical pharmacokinetic and pharmacodynamic profile of cinacalcet hydrochloride. Clinical pharmacokinetics 2009; 48(5), 303-11.