Quinine

Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

Miscellaneous MedicationsQuinine200-300mg PO HS or on HDAdminister Anytime During HD

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
3245-203-20Unchanged700.7-3.7N/AYes (N/A)

References:

  • Aronoff GR, Bennett WM, Berns JS, Brier ME, Kasbekar N, Mueller BA, et al. Drug Prescribing in Renal Failure. Philadelphia: American College of Physicians;2007.
  • DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL: http://www.drugbank.ca/drugs/DB00468
  • Midodrine. In AHFS: Drug Information. Bethesda, MD: American Society of Health-System Pharmacists; 2012.