Fentanyl
| Drug Category | Drug | IHD Dosing | Administration Timing Around HD Session |
|---|---|---|---|
| Opioids | Fentanyl | Dose as for normal renal function | Administer Anytime During HD |
Molecular Weight (Da) | Excreted Unchanged (%) | Normal Half-Life (Hours) | ESRD Half-Life (Hours) | Plasma Protein Binding (%) | Volume of Distribution (L/kg) | Dialytic Plasma Clearance (ml/min) | % Dialyzed |
|---|---|---|---|---|---|---|---|
| 336 | <10 | 2-17 (depend on dosage form) | Unchanged | 80-85 | 2-4 | N/A | 0 (high and low flux) |
References:
- Aronoff GR, Bennett WM, Berns JS, Brier ME, Kasbekar N, Mueller BA, et al. Drug Prescribing in Renal Failure. Philadelphia: American College of Physicians;2007.
- DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL: http://www.drugbank.ca/drugs/DB00813
- Joh J, Sila M, Bastani B. Nondialyzability of Fentanyl with High- Efficiency and High-Flux Membranes. Anesthesia & Analgesia. 1998;86(2):445-51.