Pantoprazole
| Drug Category | Drug | IHD Dosing |
Administration Timing Around HD Session |
|---|---|---|---|
| Proton Pump Inhibitors | Pantoprazole | 40mg Q24H | Anytime During HD |
|
Molecular Weight (Da) | Excreted Unchanged (%) | Normal Half-Life (Hours) | ESRD Half-Life (Hours) | Plasma Protein Binding (%) | Volume of Distribution (L/kg) | Dialytic Plasma Clearance (ml/min) | % Dialyzed |
|---|---|---|---|---|---|---|---|
| 383.37 | N/A | 1 | N/A | 98 | 0.16-0.34 | N/A |
2.1 (Low flux) |
References:
- Aronoff GR, Bennett WM, Berns JS, Brier ME, Kasbekar N, Mueller BA, et al. Drug Prescribing in Renal Failure. Philadelphia: American College of Physicians;2007.
- DrugBank [Online]. 2013 Feb 06 [cited 2013 Feb 06]; Available from: URL:http://www.drugbank.ca
- Kliem V, Bahlmann J, Hartmann M, Huber R, Luhmann R, Wurst W. Pharmacokinetics of pantoprazole in patients with end stage renal failure. Nephrol Dial Transplant 1998;13:1189-93.
- Pantoprazole. In: Lexi-Drugs Online. Hudson (OH): Lexi-Comp, Inc,; [updated 02/06/13; accessed 02/06/13].