Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

Antiemetics Metoclopramide 5mg PO/IV Q6H PRN Anytime During HD

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
299.8 10-22 2.5-4 14-15 40 2-3.4 91.0 ± 15.9

minimal (Low flux)


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    • DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL:
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