Sevelamer

Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

Metabolic Bone Disease MedicationsSevelamerDose based on blood workAdminister with meals

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
150<0.02N/AN/AN/AN/AN/AN/A

References:

  • DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL: http://www.drugbank.ca/drugs/DB00658
  • Goldsmith D, Scott L, Cvetkovi R et al. Sevelamer Hydrochloride - A Review of its Use for Hyperphosphataemia in Patients with End-Stage Renal Disease on Haemodialysis. Drugs 2008; 68(1), 85-104.