Midodrine
Drug Category | Drug | IHD Dosing | Administration Timing Around HD Session |
---|---|---|---|
Miscellaneous Medications | Midodrine | Dose as per hypotension requirements; usually 2.5-10mg PO at the start of HD for intradialytic hypotension | Administer at the Start of HD |
Molecular Weight (Da) | Excreted Unchanged (%) | Normal Half-Life (Hours) | ESRD Half-Life (Hours) | Plasma Protein Binding (%) | Volume of Distribution (L/kg) | Dialytic Plasma Clearance (ml/min) | % Dialyzed |
---|---|---|---|---|---|---|---|
254 | 75-80 | 0.5 | N/A | Minimal | <1.6 | N/A | Yes (N/A) |
References:
- DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL: http://www.drugbank.ca/drugs/DB00211
- Midodrine. In AHFS: Drug Information. Bethesda, MD: American Society of Health-System Pharmacists; 2012