Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

Miscellaneous MedicationsMidodrineDose as per hypotension requirements; usually 2.5-10mg PO at the start of HD for intradialytic hypotensionAdminister at the Start of HD

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
25475-800.5N/AMinimal <1.6N/AYes (N/A)


  • DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL: http://www.drugbank.ca/drugs/DB00211
  • Midodrine. In AHFS: Drug Information. Bethesda, MD: American Society of Health-System Pharmacists; 2012