Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

AntibioticsPiperacillin/Tazobactam2.25-4.5g IV Q12HAdminister Post-HD

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
518/30075-90/650.8-1.5/13.3-5.1/1730/220.18-0.30/0.2146.3-78.2/94.610-65/37-39 (low flux)


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