Streptomycin
| Drug Category | Drug | IHD Dosing | Administration Timing Around HD Session |
|---|---|---|---|
| Antibiotics | Streptomycin | 1-2g IV Q72-96H | Administer Post-HD |
Molecular Weight (Da) | Excreted Unchanged (%) | Normal Half-Life (Hours) | ESRD Half-Life (Hours) | Plasma Protein Binding (%) | Volume of Distribution (L/kg) | Dialytic Plasma Clearance (ml/min) | % Dialyzed |
|---|---|---|---|---|---|---|---|
| 582 | 80 | 2.5 | 100 | 35 | 0.26 | N/A | N/A |
References:
- Akaho E, Maekawa T, Uchinashi M, Kanamori R. A Study of Streptomycin Blood Level Information of Patients Undergoing Hemodialysis. Biopharmaceutics & Drug Disposition 2002; 23, 47-52.
- Aronoff GR, Bennett WM, Berns JS, Brier ME, Kasbekar N, Mueller BA, et al. Drug Prescribing in Renal Failure. Philadelphia: American College of Physicians;2007.
- DrugBank [Online]. 2012 Apr 12 [cited 2012 May 6]; Available from: URL: http://www.drugbank.ca/drugs/DB01082
- Launay-Vacher V, Izzedine H, Deray G. Pharmacokinetic considerations in the treatment of tuberculosis in patients with renal failure. Clinical pharmacokinetics 2005; 44(3), 221-35.